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              當(dāng)前位置:首頁資料下載XBP1抗原,細(xì)胞核轉(zhuǎn)錄因子X盒結(jié)合蛋白抗原

              XBP1抗原,細(xì)胞核轉(zhuǎn)錄因子X盒結(jié)合蛋白抗原

              發(fā)布時(shí)間:2024/11/7點(diǎn)擊次數(shù):34

              Recombinant human XBP1   

              X box-binding protein-1; XBP-1; XBP2; Tax responsive element binding protein 5; TREB5; X box binding protein 2; XBP 1; XBP2; XBP1_HUMAN; X-box-binding protein 1, cytoplasmic form; X-box-binding protein 1, luminal form; X-box-binding protein 1 in isoform 2.           

              濃度:1mg/ ml

              來源:Recombinant Human

              純度:≥95% SDS-PAGE

              表達(dá)系統(tǒng):Escherichia coli

              標(biāo)簽:His tag   

              蛋白長度:Full length protein

              內(nèi)毒素水平:<1.000 Eu/µg

              純化方法:HPLC

              應(yīng)用:SDS-PAGEWestern blotELISA

              Biological activity,immunology research

              保存:-20

              保質(zhì)期:1

              This gene encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box. This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter. It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator. It has been found that upon accumulation of unfolded proteins in the endoplasmic reticulum (ER), the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the endonuclease inositol-requiring enzyme 1 (IRE1). The resulting loss of 26 nt from the spliced mRNA causes a frame-shift and an isoform XBP1(S), which is the functionally active transcription factor. The isoform encoded by the unspliced mRNA, XBP1(U), is constitutively expressed, and thought to function as a negative feedback regulator of XBP1(S), which shuts off transcription of target genes during the recovery phase of ER stress. A pseudogene of XBP1 has been identified and localized to chromosome 5. 



              多克隆抗體

              產(chǎn)品名稱:Rabbit Anti-XBP1 antibody

              Rabbit Anti-XBP1 

              別名:X box-binding protein-1; XBP-1; XBP2; Tax responsive element binding protein 5; TREB5; X box binding protein 2; XBP 1; XBP2; XBP1_HUMAN; X-box-binding protein 1, cytoplasmic form; X-box-binding protein 1, luminal form; X-box-binding protein 1 in isoform 2.              

              來源:Rabbit

              克隆類型:Polyclonal

              濃度:1mg/ml

              亞型:IgG

              反應(yīng):Human,Mouse,Rat (predicted: Cow,Chicken)

              應(yīng)用: WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

              理論分子量:29kDa

              免疫原:KLH conjugated synthetic peptide derived from human XBP1

              保存:-20
              保質(zhì)期:1

               

               單克隆抗體

              產(chǎn)品名稱:Anti-XBP1 antibody

              Mouse Anti-XBP1

              別名:X box-binding protein-1; XBP-1; XBP2; Tax responsive element binding protein 5; TREB5; X box binding protein 2; XBP 1; XBP2; XBP1_HUMAN; X-box-binding protein 1, cytoplasmic form; X-box-binding protein 1, luminal form; X-box-binding protein 1 in isoform 2.                

              來源:Mouse

              克隆類型:Monoclonal

              濃度:1mg/ml

              亞型:IgG

              反應(yīng):Human

              應(yīng)用: WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500  

              反應(yīng):  Human

              理論分子量:29kDa

              免疫原:KLH conjugated synthetic peptide derived from human XBP1

              保存:-20
              保質(zhì)期:1

              This gene encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box. This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter. It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator. It has been found that upon accumulation of unfolded proteins in the endoplasmic reticulum (ER), the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the endonuclease inositol-requiring enzyme 1 (IRE1). The resulting loss of 26 nt from the spliced mRNA causes a frame-shift and an isoform XBP1(S), which is the functionally active transcription factor. The isoform encoded by the unspliced mRNA, XBP1(U), is constitutively expressed, and thought to function as a negative feedback regulator of XBP1(S), which shuts off transcription of target genes during the recovery phase of ER stress. A pseudogene of XBP1 has been identified and localized to chromosome 5. 

               

               



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              精品乱子伦一区二区三区_亚洲精品乱码久久久久久按摩_亚洲久久久久久久_日韩av亚洲欧美一区二区三区_来一水AV@lysav
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